The specificity and patterns of staining in human cells and tissues of p16INK4a antibodies demonstrate variant antigen binding.
The validity of the identification and classification of human cancer using antibodies to detect biomarker proteins depends upon antibody specificity.Antibodies that bind to the tumour-suppressor protein p16INK4a are widely used for cancer diagnosis and research.In this study we examined the specificity of four commercially available anti-p16INK4a